You are unique – Does your gene editing treatment need to be too?

Many diseases are caused by genetic mutations. Small mutations can cause certain cancers, some cases of blindness, influence heart disease, and many other pathologies. A new and powerful technology called CRISPR-Cas9 aims to correct for these genetic mutations by cutting out a piece of malfunctioning DNA, and replacing it with a piece of genetic material that functions correctly. Biologists first discovered CRISPR-Cas9 in bacteria. Through careful … Continue reading You are unique – Does your gene editing treatment need to be too?

Colonies 1 and 2

No one likes to be in crowded spaces, so when colonies reach a critical cell density, cells within the colony begin to lyse, dramatically changing the architecture of the colony. The colony on the left is a wild-type colony, while the colony on the right is a genetic mutant that exhibits an autolytic phenotype, that is the bacterium’s own enzymes “eat up” its cells. The … Continue reading Colonies 1 and 2

Black Hole Burps: Particle Absorption and Emission in Supermassive Black Holes

Black holes are fascinating objects to study because we can use them to learn more about about astronomy, cosmology, and gravity. Black holes are super-massive and super-dense objects in the universe. Because of these properties, they produce strong gravitational and electromagnetic forces that suck nearby objects in. After ‘eating’ all this extraneous matter, the black hole has energy to spare and then ‘burps’, emitting high-energy … Continue reading Black Hole Burps: Particle Absorption and Emission in Supermassive Black Holes

Arctic Apples: A fresh new take on genetic engineering

by Allison Baker figures by Lillian Horin The Arctic apple is the juiciest newcomer to produce aisles. It has the special ability to resist browning after being cut (Figure 1), which protects its flavor and nutritional value. Browning also contributes to food waste by causing unappealing bruising on perfectly edible apples. Food waste, especially for fruits and vegetables, is a major problem worldwide; nearly half … Continue reading Arctic Apples: A fresh new take on genetic engineering

Regeneration: What the axolotl can teach us about regrowing human limbs

by Garrett Dunlap figures by Rebecca Senft Limb loss affects nearly 2 million people in the United States alone. While many instances are related to traumatic events like car accidents, the majority of limb loss cases are caused by diseases that affect the body’s blood vessels. One such disease is diabetes, in which gradual declines in blood flow to a patient’s lower extremities can eventually … Continue reading Regeneration: What the axolotl can teach us about regrowing human limbs

Colonies on a Plate

A single bacterial cell is invisible to the naked eye. As that single cell grows and divides into new cells, however, it forms a visible pile of bacteria. In microbiology, we call this pile of bacteria a colony. A colony’s appearance can indicate a lot about the bacterial cells within, such as how they utilize nutrients, if they carry genetic mutations, and how the bacterial … Continue reading Colonies on a Plate

Fighting the Opioid Addiction Crisis: Can scientists cure it?

by Mary May figures by Neal Akatsuka An estimated 59,000 to 65,000 Americans died due to drug overdoses last year, which is more than the number of deaths from HIV/AIDS at the peak of the epidemic in 1995 and more than the total number of American deaths in the Vietnam War. The over-prescription of pain-relieving opioid drugs like morphine and oxycodone has created another epidemic … Continue reading Fighting the Opioid Addiction Crisis: Can scientists cure it?

Can we locate bacteria by listening to them?

An ultrasound is probably most popularly recognized as a doctor’s tool to peer into the womb and take a look at a growing fetus during a woman’s pregnancy. But what if sound could be used to take a look at even smaller things – like the microorganisms in your gut? Mikhail Shapiro’s research group at the California Institute of Technology has been able to track … Continue reading Can we locate bacteria by listening to them?