Mining DNA for Disease Prediction: the polygenic risk score

by Alex Yenkinfigures by Allie Elchert Long before the completion of the Human Genome Project, scientists knew that many common diseases had a genetic component. However, there was debate about the architecture of these genetic effects: were there a few high-effect mutations or thousands of tiny effect mutations spread throughout the genome? Now, in the full swing of the genomics revolution, we can see that … Continue reading Mining DNA for Disease Prediction: the polygenic risk score

Understanding Ownership and Privacy of Genetic Data

by Julian Segert figures by Aparna Nathan In Mountain View, California, near the headquarters of Facebook and Google, lies 23andMe, a company that set out to make genetic testing approachable and affordable for the general public. The company started with the goal of providing risk assessments for genetic diseases, but has recently gained more popularity by offering insights into geographical ancestry. 23andMe is unique among … Continue reading Understanding Ownership and Privacy of Genetic Data