Fighting Fire with Fire: Killing bacteria with virus

by Veerasak “Jeep” Srisuknimit figures by Jovana Andrejevic Our time with antibiotics is running out. In 2016, a woman in Nevada died from a bacterial infection caused by Klebsiella pneumoniae that was resistant to all available antibiotics. Bacteria that is resistant to colistin, an antibiotic of last resort, has been discovered on pig farms in China. Bacteria have been evolving to resist antibiotics faster than … Continue reading Fighting Fire with Fire: Killing bacteria with virus

Colonies 4

To get around, Pseudomonas aeruginosa bacterium use a number of motility strategies, such as twitching and gliding. In this image, we see a special kind of bacterial motility behavior known as swarming, where a mass of bacteria moves collectively across a surface.  This is an example of singled celled bacterial species acting in a multicellular way. For a group of cells to swarm, the bacterium … Continue reading Colonies 4

Can We Treat Heroin Addiction and HIV with a Single Vaccine?

by Fernanda Ferreira figures by Brad Wierbowski Every day 140 Americans die from an opioid overdose. To confront the crisis, not only must opioid addiction treatment become more readily available, but new and improved forms of treatment must also be developed. Dr. Carl Alving, whose life work has been to develop an HIV vaccine, never planned on investigating novel systems for treating opioid addiction. But … Continue reading Can We Treat Heroin Addiction and HIV with a Single Vaccine?

Remote Brain Stimulation: A new treatment for Parkinson’s disease?

by Anqi Zhang figures by Daniel Utter What do you think of the idea of inserting a long metal wire into your brain? That’s what doctors have done to ease the symptoms of Parkinson’s disease over the past 20 years. Sound scary? A new technique called temporal interference stimulation is exploring the possibility of achieving the same effects by attaching electrical stimulators to the outside of … Continue reading Remote Brain Stimulation: A new treatment for Parkinson’s disease?

Colonies 3

It may be hard to believe, but this sea of shiny, donut-shaped colonies are Pseudomonas aeruginosa colonies. These Pseudomonas colonies have a genetic mutation that causes many of the bacteria’s genes to be shut off. The donut-shape of these colonies may indicate a two-step growth phase where the younger cells on the outside edge of the colony grow towards more nutrients while the older cells in … Continue reading Colonies 3

Colonies 1 and 2

No one likes to be in crowded spaces, so when colonies reach a critical cell density, cells within the colony begin to lyse, dramatically changing the architecture of the colony. The colony on the left is a wild-type colony, while the colony on the right is a genetic mutant that exhibits an autolytic phenotype, that is the bacterium’s own enzymes “eat up” its cells. The … Continue reading Colonies 1 and 2

Arctic Apples: A fresh new take on genetic engineering

by Allison Baker figures by Lillian Horin The Arctic apple is the juiciest newcomer to produce aisles. It has the special ability to resist browning after being cut (Figure 1), which protects its flavor and nutritional value. Browning also contributes to food waste by causing unappealing bruising on perfectly edible apples. Food waste, especially for fruits and vegetables, is a major problem worldwide; nearly half … Continue reading Arctic Apples: A fresh new take on genetic engineering

Regeneration: What the axolotl can teach us about regrowing human limbs

by Garrett Dunlap figures by Rebecca Senft Limb loss affects nearly 2 million people in the United States alone. While many instances are related to traumatic events like car accidents, the majority of limb loss cases are caused by diseases that affect the body’s blood vessels. One such disease is diabetes, in which gradual declines in blood flow to a patient’s lower extremities can eventually … Continue reading Regeneration: What the axolotl can teach us about regrowing human limbs

Colonies on a Plate

A single bacterial cell is invisible to the naked eye. As that single cell grows and divides into new cells, however, it forms a visible pile of bacteria. In microbiology, we call this pile of bacteria a colony. A colony’s appearance can indicate a lot about the bacterial cells within, such as how they utilize nutrients, if they carry genetic mutations, and how the bacterial … Continue reading Colonies on a Plate