Glioblastoma is one of the most deadly brain cancers because it is nearly impossible to destroy the cause of the cancer: cancerous stem cells. However, scientists are using Zika’s preference for stem cells to target and eliminate the cancerous stem cells in adults. The preliminary study shows the viability of this method, but more thorough research and a PR campaign may be necessary before Zika treatments for brain cancer can become standard protocol. Continue reading Could Zika become a treatment for brain cancer?
The image above shows a developing zebrafish eye 3 days after fertilization. From this perspective, we are staring directly into the eye of the zebrafish and can appreciate both its beauty and its complexity. At this stage, the cells that comprise and surround the zebrafish eye display an incredible organization. The dark circle that appears to be a hole in the middle of the eye … Continue reading Perspective I
The brain is arguably the most complex organ in the human body and understanding its structure could help explain a fundamental mystery of human existence: consciousness. The brain is composed of billions of specialized cells called neurons, which communicate with each other via electrical and chemical signals. Neurons are responsible for processes ranging from vital life functions to the ability to walk, talk remember, … Continue reading One Neuron to Rule Them All?
The Drosophila neuromuscular junction is a beautiful and yet powerful model synapse for in vivo studies of development, physiology, cell biology and plasticity. This illustration by Saskia Van Vactor shows a field of ventral longitudinal body wall muscles in red, as if stained with phalloidin to highlight filamentous actin, the main protein building block of muscle. Against this background, several branches of intersegmental nerve extend … Continue reading Branched synaptic arbor in fillet
Researchers have created the most detailed general map of the brain to date by scanning the brains of 1200 people. After recording detailed imaging of the subjects’ brain activity as they performed a variety of mental tasks, the information was used to ‘teach’ a computer to identify spatial ‘regions’ of related activity. These regions span the brain, creating a 3D, puzzle-like map. Also called a … Continue reading New Detailed Brain Map Could Aide Future Understanding
The brain is made of up billions of neurons and even more connections between neurons. We can get an idea of how neurons are connected across the human brain using a type of brain scan called diffusion-weighted magnetic resonance imaging (dMRI). How does dMRI work? It actually measures the direction that water moves throughout the brain. Sometimes, water can move in all directions equally easily – like … Continue reading The Brain is a Series of Tubes
Image contributed by Yu Wang, a third year graduate student at Harvard Medical School. Glial cells support the proper function of neuronal cell types and are also responsible for cleaning up cell debris such as leftover neurotransmitter molecules (what neurons use to communicate with each other). Certain types of glia, called microglia, function as the first line of defense in immune-privileged places such as the … Continue reading Retinal Corona