Our bodies contain numerous cell types that look drastically different and perform various functions that allow us to eat, breathe, move, and reproduce. While all cells have the same DNA as a “blueprint”, their working set of proteins can vary drastically. The process of making protein from DNA is known as the “central dogma”. However, it is not a linear step, but instead requires two … Continue reading Central Dogma
Early-stage research has identified a compound that stops pesky colds in their tracks – useful as a potential cold cure. Although adults are bothered by an average of 2-3 colds per year, colds can “cause serious complications in people with conditions like asthma and [chronic obstructive pulmonary disease] (COPD),” lead researcher Edward Tate, Chemical Biology Professor at the Imperial College London, told ScienceDaily. “A drug … Continue reading A Future Cure for the Common Cold?
by Jessalyn Ubellacker figure by Jovana Andrejevic Between September 1999 and June 2000, the first human genome was sequenced. Since then, scientists have learned not only to read the human genome, but also to manipulate it, offering unprecedented opportunities to improve human health through genetic alterations. One example of this is gene drive technology, which circumvents classical inheritance patterns to ‘drive’ the presence of particular … Continue reading Buckle Up for Gene Drives of the Future!
by Alyson Warr figures by Olivia Foster One in eight women in the United States will develop breast cancer in her lifetime. This statistic makes breast cancer the leading cancer diagnosis for women in the US. With such staggering numbers, a focus on prevention is key: how can we stop breast cancer before it starts? One way is to develop fast and convenient methods of … Continue reading Using Genetics to Fight Cancer: The pros and cons of direct-to-consumer testing
Before cells divide, they have to unwind their chromosomes, copy of all of their DNA, and then wrap the DNA backup into chromosomes. When this process happens, cells often lose a little bit of DNA from the tips of their chromosomes. An enzyme, called telomerase, can help repair chromosomes by adding that DNA back onto the ends. Scientists are interested in telomerase because inhibiting it … Continue reading Cellular Secrets: Getting a look at how cells repair DNA
It is 2018, and we are well on our way towards curing cancer. Yet, as we look around, we find another nightmare haunting our society that is as formidable, if not more so, as it has been for centuries. That nightmare is opioid addiction. Overcoming opioid addiction is notoriously difficult, because of the excruciating symptoms associated with the withdrawal process, during which the only aid … Continue reading The FDA Approves the First Non-Opioid Drug to Ease Opioid Withdrawal Symptoms
by Christopher Gerry figures by Abagail Burrus A few weeks ago, a nurse took six gallons of blood out of my left arm; my body only holds about a gallon and a half of blood, so I wouldn’t be here if she had decided to keep it. The blood that was continuously returning to my right arm, however, was missing an important ingredient: peripheral blood … Continue reading Never Tell Me the Odds: A first-hand account of blood stem cell donation
For the first time, an inherited disorder has been reversed in babies before birth. “There are a number of conditions for which we would seek treatment in utero, but traditionally these have been non-genetic, non-inherited conditions,” Dr. Maisa Feghali, an assistant professor of maternal fetal medicine at the University of Pittsburgh, who was not involved in this study, told STAT. The disease, X-linked hypohidrotic ectodermal … Continue reading Successful treatment of a rare genetic disorder in the womb
by Fernanda Ferreira figures by Daniel Utter There are tens of thousands of buildings in São Paulo, the largest city in the Western hemisphere and Brazil’s financial center. From the sky, São Paulo looks like a fossilized forest of concrete trees. From the ground, it’s a pulsing behemoth, every avenue crammed with cars and people. The urban sprawl of Metropolitan São Paulo engulfs 39 municipalities … Continue reading Disease Never Sleeps: Yellow fever and the importance of vaccine stockpiles in emergency epidemic prevention
Is this apple safe to eat? Did that course of antibiotics work? To answer these types of questions we often need to know how to find and count illness-causing bacteria. Several bacteria counting techniques already exist. However, these approaches are slow and sensitive to laboratory conditions. Sam Nugen and his team from Cornell University are streamlining this process using a type of virus called phages, … Continue reading Viruses to the Rescue: Can we use viruses to find bacteria in our environment?