by Francesca Tomasi figures by Olivia Foster Rhoades Argonaut. Idéfix. Flamenco. These words invoke movement: the ancient Greek Argonauts were a band of adventurous sailors famous for their epic quests. Meanwhile, Idéfix is the name of an adventure-loving dog in the French Astérix comic book series. And finally, flamenco conjures images of vivacious dancers. You would think the similarities between Greek mythology, French comic books, and … Continue reading Transposons: Your DNA that’s on the go
The placebo effect is a puzzling phenomenon. Placebos (sugar pills or saline solutions secretly substituted for actual drugs) are commonly used in clinical trials to set a baseline against which to measure the effects of a drug. However, people in the placebo group will often show improvements alongside the treatment group. The fact that an inactive substance, such as a sugar pill, can lead to … Continue reading Your Personality May Determine How You Respond to Placebo Pills
Chemotherapy is a common cancer treatment, using drugs to destroy cancer cells. However, cancer cells can develop resistance to chemotherapy drugs by developing “efflux pumps”, pumps in the cell membrane that work to actively expel the chemotherapy drugs from the tumor cells. Shana Kelley and her team in University of Toronto developed nanomaterials that can deliver drugs into cancer cells and suppress their drug resistance. … Continue reading Nanomaterials as cancer treatment: overcoming drug resistance in chemotherapy
Infectious diseases — including HIV, tuberculosis, and malaria — are a leading cause of death worldwide, particularly in low income countries and among young children. A new study found that the vaccines aimed to prevent many of the world’s most deadly diseases may not be developed any time soon. The study, funded by the Gates Foundation and the Swiss Agency for Development and Cooperation, focused on 538 … Continue reading Vaccines for World’s Most Deadly Infectious Diseases Unlikely
by Ryan McGillicuddy figures by Sean Wilson When I think of the challenges associated with exploring space, I usually think of explosive rockets, speeding meteorites, deadly radiation, and the empty vacuum of space. Admittedly, my first worry about space is not the freezing temperatures. But in reality, temperature control in space is a challenge that NASA constantly faces. For example, the sun-facing side of the … Continue reading How to Keep Electronics Warm in Space? Use Hot Wax
by Jemila C Kester, PhD figures by Rebecca Clements In the Seinfeld episode “The Stranded,” Jerry is choosing between two cold medicines. “This is quick-acting, but this is long-lasting,” he notes. “When do I need to feel good, now or later?” We often face a similar dilemma when choosing a particular diet as weight-loss “medicine.” With a third of American adults overweight, there’s a veritable … Continue reading Eating for a Trillion: Can your microbiome be the key to long-lasting weight loss?
In an exciting step forward, dogs with Duchenne muscular dystrophy (DMD) were treated with the CRISPR genome editor to restore production of the missing protein responsible for the disease. After more studies to prove it is safe and effective long-term, this has the potential to move into clinical trials as a DMD therapy. “[The dogs] showed obvious signs of behavioral improvement – running, jumping – … Continue reading Dogs with muscular dystrophy receive CRISPR treatment: What does this mean for humans?
by Daniel Ang figures by Aparna Nathan Particle physics says that the universe shouldn’t exist. This is a radical claim! But if the current theories that underlie particle physics are correct and complete, then the Big Bang that birthed the universe would have simply resulted in a massive flash of light. Nothing else would remain – no stars, planets or galaxies. And neither you nor … Continue reading The Frustrating Search for New Physics
Antibiotics, while life-saving, can also wreak havoc on healthy systems. The drugs work by attacking the protein-synthesizing center (ribosomes) in bacteria. When the ribosomes in human cells are mistaken for bacterial ribosomes, antibiotics can cause a range of side effects from nausea to kidney failure. To understand what conditions cause healthy cells to be attacked, scientists are implementing novel imagining techniques to study interactions between … Continue reading Biologists and Physicists Work Together to Image Subcellular Interactions Like Never Before
by Madeleine Jennewein figures by Rebecca Senft Across the United States, nuclear waste is accumulating in poorly maintained piles. 90,000 metric tons of nuclear waste requiring disposal are currently in temporary storage. The United States, however, has yet to construct a long-term storage solution for this waste, leaving the nuclear material vulnerable to extreme weather events such as hurricanes, rising sea levels, and wildfire. Nuclear … Continue reading Looking for a Trash Can: Nuclear waste management in the United States