COVID-19: from treatment to prevention

by Apurva Govande figures by Tal Scully COVID-19, the disease caused by the newly discovered virus SARS-CoV-2, is a national emergency. We need a vaccine to prevent severe outcomes of disease, to successfully combat future outbreaks of this virus, and to ensure that businesses and schools can safely reopen. Until one is available, healthcare professionals can mitigate symptoms while deploying existing drugs that may show … Continue reading COVID-19: from treatment to prevention

CRISPR 2.0: Genome engineering made easy as A-B-C

CRISPR 2.0 is causing quite the ruckus in the scientific community. Why? Imagine that you had written a note in permanent marker, but later decided you wanted to change a single word. Without the ability to erase, your options would be limited, and further changes might make the note illegible. New CRISPR technologies, or “base editors,” behave as molecular erasers. These molecular erasers enable you to very precisely … Continue reading CRISPR 2.0: Genome engineering made easy as A-B-C

The Hidden Genetic Code

by Amir Bitran figures by Daniel Utter Proteins, the molecules that sustain all life, are similar to cars and other machines in an important way: they require a specific, well-defined structure to function. Obviously, a random pile of car parts cannot be driven. And similarly, a protein that is not assembled correctly cannot perform crucial tasks like producing energy, supporting cell structure, and generating electric signals. In … Continue reading The Hidden Genetic Code

Epigenetics in Plant Breeding: Hard Science, Soft Tool

by Pierre Baduel figures by Kaitlyn Choi Summary: The legality of genetically modified organisms (GMOs) remains a controversial issue around the world, especially in Europe. Recent discoveries in the field of epigenetics, or heritable information not encoded in the DNA, have revealed promising alternatives to genetic engineering. As reported in Proceedings of the National Academy of Sciences (PNAS) this year, a team of British researchers … Continue reading Epigenetics in Plant Breeding: Hard Science, Soft Tool