RNA plays a newly discovered role in the development of cancer

by Carlos Moralesfigures by Shreya Mantri Our cells perform extraordinary functions using information stored in their genetic material, known as DNA. Changes in DNA, known as mutations, can make cells behave erratically, which may lead to cancer. But how does cancer begin? A new model proposes that RNA — the molecular link between DNA and proteins — is at the heart of this phenomenon. How … Continue reading RNA plays a newly discovered role in the development of cancer

Dissecting cancer complexity across space and time

by Jackson Weirfigures by Jasmin Joseph-Chazan Why is cancer so difficult to cure? Why do available treatments only help a subset of patients? Why are some cancers more aggressive than others? These are questions that clinicians, scientists, and the public have pondered for generations. As it turns out, the answers are complicated because cancer biology is complicated. Luckily, new tools and technologies are helping us … Continue reading Dissecting cancer complexity across space and time

Mutation Madness: How and why SARS-CoV-2 keeps changing

by Sophia Swartzfigures by Shreya Mantri The first reports of a mysterious, pneumonia-like illness surfaced in early December 2019. Fast-forward to 2021, and the culprit—SARS-CoV-2, a virus a thousand times smaller than a speck of dust—has sickened more than 111 million people, infected all seven continents, and killed approximately 2.5 million.  The toll of COVID-19 is heart-wrenching and borders on dystopian. Our pandemic present is … Continue reading Mutation Madness: How and why SARS-CoV-2 keeps changing

COVID-19: from treatment to prevention

by Apurva Govande figures by Tal Scully COVID-19, the disease caused by the newly discovered virus SARS-CoV-2, is a national emergency. We need a vaccine to prevent severe outcomes of disease, to successfully combat future outbreaks of this virus, and to ensure that businesses and schools can safely reopen. Until one is available, healthcare professionals can mitigate symptoms while deploying existing drugs that may show … Continue reading COVID-19: from treatment to prevention