An Introduction to Ribosomes: Nature’s busiest molecular machines

by Francesca Tomasifigures by Jovana Andrejevic  Right now, the world is eagerly awaiting clinical trial data for two candidate COVID-19 vaccines known as mRNA vaccines. mRNA stands for “messenger RNA,” referring to the molecule that the vaccine delivers to our bodies. Once the vaccine enters our cells, the mRNA tells them exactly how to build a piece of the SARS-CoV-2 virus. The vaccine itself cannot … Continue reading An Introduction to Ribosomes: Nature’s busiest molecular machines

Biologists and Physicists Work Together to Image Subcellular Interactions Like Never Before

Antibiotics, while life-saving, can also wreak havoc on healthy systems. The drugs work by attacking the protein-synthesizing center (ribosomes) in bacteria. When the ribosomes in human cells are mistaken for bacterial ribosomes, antibiotics can cause a range of side effects from nausea to kidney failure. To understand what conditions cause healthy cells to be attacked, scientists are implementing novel imagining techniques to study interactions between … Continue reading Biologists and Physicists Work Together to Image Subcellular Interactions Like Never Before

The Hidden Genetic Code

by Amir Bitran figures by Daniel Utter Proteins, the molecules that sustain all life, are similar to cars and other machines in an important way: they require a specific, well-defined structure to function. Obviously, a random pile of car parts cannot be driven. And similarly, a protein that is not assembled correctly cannot perform crucial tasks like producing energy, supporting cell structure, and generating electric signals. In … Continue reading The Hidden Genetic Code