Vision you can’t see: How the brain senses the time of day

by Nicolai Penafigures by Jasmin Joseph-Chazan Toward the end of the 20th century, the intricate biology of how the eye produces visual information was thought to be well understood– a combination of sensors and circuits in the eye extract features of visual scenes. This information is conveyed from the eye to the brain by specialized neurons that physically connect the two structures (Figure 1, blue). … Continue reading Vision you can’t see: How the brain senses the time of day

Are microglia the hero or the villain in Alzheimer’s disease?

by Gizem Terzioglufigures by MJ Park Alzheimer’s disease is a progressive neurodegenerative disorder that affects millions of people worldwide, and despite years of research efforts, there is still no cure. However, recent studies have highlighted the crucial roles of microglia, the resident immune cells of our brain, in the development and progression of Alzheimer’s disease. But the question remains: do microglia defend our brain against … Continue reading Are microglia the hero or the villain in Alzheimer’s disease?

Neuroplasticity: how lost skills can be regained after injury or illness

by Beatrice Awasthifigures by Shreya Mantri Loss of motor or cognitive skills can be a devastating after-effect of injury or illness. When things that used to feel easy suddenly feel impossible, a full recovery can appear completely out of reach. In many cases, persisting symptoms of pain, weakness, and fatigue can be due to dysfunction of the nervous system. Fortunately, the nervous system has an … Continue reading Neuroplasticity: how lost skills can be regained after injury or illness

Brain Hijackers: How cancer manipulates the brain to help it grow

by Hannah Farnsworthfigures with Xiaomeng Han Most people know someone in their life who has been impacted by cancer, and a staggering 40% of us will be diagnosed with cancer in our lifetimes. Despite the prevalence of cancer in the general population, there are many types of cancer that still lack effective treatments. One such form of cancer is a type of brain tumor called … Continue reading Brain Hijackers: How cancer manipulates the brain to help it grow

How does your brain make you feel sick? 

by Courtney Whildenfigures by Arianna Lord Imagine this: it’s the peak of winter, and you wake up not feeling well. You touch your face, it feels warm, and your thermometer tells you that you have a fever. As the day goes on, you don’t have much of an appetite, you’re exhausted, and you crave the warmth of a blanket and a cup of hot tea. … Continue reading How does your brain make you feel sick? 

What it Takes to Make a Brain: Cellular diversity in cortical development

by Olubusola Olukoyafigures by Corena Loeb Our ability to take in information from the world around us, make inferences, and execute appropriate reactions is generated by our brains. The brain, which weighs about 1.5 kilograms in the average adult, takes up 20% of our body’s energy expenditure to power a network of roughly 86 billion cells. Ongoing research in the field of neuroscience utilizes various … Continue reading What it Takes to Make a Brain: Cellular diversity in cortical development

Dissecting cancer complexity across space and time

by Jackson Weirfigures by Jasmin Joseph-Chazan Why is cancer so difficult to cure? Why do available treatments only help a subset of patients? Why are some cancers more aggressive than others? These are questions that clinicians, scientists, and the public have pondered for generations. As it turns out, the answers are complicated because cancer biology is complicated. Luckily, new tools and technologies are helping us … Continue reading Dissecting cancer complexity across space and time