Tag: Ketamine

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Sensitization: Why everything might hurt when it looks like nothing is wrong

by Beatrice Awasthifigures by Allie Elchert Millions of Americans struggle with chronic pain. While the pain sometimes has a clear source—for instance, an arthritic joint or a damaged tendon—oftentimes, people feel pain without any obvious signs of damage at all. This can be extremely distressing, as such patients may deal with stigmatization or invalidation of their pain by others who suggest that the pain is … Continue reading Sensitization: Why everything might hurt when it looks like nothing is wrong

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FDA approves first ketamine-based antidepressant

Depression is the leading cause of disability worldwide, affecting more than 300 million people of all ages around the world. The most commonly used antidepressant medications are called selective serotonin reuptake inhibitors (SSRIs). Only about  one third of people with major depressive disorder achieve remission after treatment with SSRIs. When the first medication doesn’t work, the next steps are usually to switch to or add another … Continue reading FDA approves first ketamine-based antidepressant

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Down, but not out: Developments in depression research

by Emily Ricq Depression affects 15 million Americans and is characterized by debilitating feelings of sadness or emptiness that interfere with the ability to lead and enjoy life [1]. The substantial personal and public health burden imposed by depression has motivated decades of intensive research by scientists, clinicians, therapists, and pharmaceutical companies alike, yet the biology underlying the cause (or causes) of the disease and … Continue reading Down, but not out: Developments in depression research

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