Current polio vaccines have been successful in nearly eradicating polio in the world. Unfortunately, there have been emerging cases of polio in recent years. To combat this, scientists have designed a new oral poliovirus vaccine that could result in a new and safer polio vaccine. Continue reading Redesigning the polio vaccine – Lessons from evolution
by Isabella Grabski figures by Jovana Andrejevic Clinical trials are critical to study the safety and effectiveness of new drugs, but they are no small endeavor. The cost of a clinical trial can range anywhere from $7 million to over $50 million, and they can take up to a decade to fully complete. Not only can this represent a substantial strain on a pharmaceutical company, it also … Continue reading Virtual Clinical Trials: Testing new drugs from afar
Doctors at Boston Children’s Hospital engineered a unique medicine to treat a young girl’s disease: they reverse engineered a blocker from her DNA to inhibit the gene causing the disease. Continue reading Individual Genetic Medicine Helps Treat Genetic Disease
Researchers at McMaster University have developed a novel method for stabilizing vaccines, removing the strict requirement that the components be maintained within a specific low temperature range from development through delivery. The technique is based on drying the vaccines using two FDA-approved sugars and was shown to be successful in preserving vaccine effectiveness at elevated temperatures for twelve weeks. While it must still be validated on other vaccines, this method could be a major step toward cheap, accessible immunization in developing areas. Continue reading A Sweet Solution for Preserving Vaccines
Depression is the leading cause of disability worldwide, affecting more than 300 million people of all ages around the world. The most commonly used antidepressant medications are called selective serotonin reuptake inhibitors (SSRIs). Only about one third of people with major depressive disorder achieve remission after treatment with SSRIs. When the first medication doesn’t work, the next steps are usually to switch to or add another … Continue reading FDA approves first ketamine-based antidepressant
In 2018, approximately 5.7 million Americans are living with Alzheimer’s dementia, a number that is expected to double within the next 30 years. Alzheimer’s disease causes memory loss, mood changes, and eventually difficulty speaking, swallowing, and walking. Currently, no medication exists that can slow or stop the progression of Alzheimer’s disease and no new treatments have been approved by the FDA in more than 15 … Continue reading Hope for Alzheimer’s patients? The first positive clinical trial results in years
It is 2018, and we are well on our way towards curing cancer. Yet, as we look around, we find another nightmare haunting our society that is as formidable, if not more so, as it has been for centuries. That nightmare is opioid addiction. Overcoming opioid addiction is notoriously difficult, because of the excruciating symptoms associated with the withdrawal process, during which the only aid … Continue reading The FDA Approves the First Non-Opioid Drug to Ease Opioid Withdrawal Symptoms
With peanuts being the most common children’s food allergen and the rising prevalence of allergies, discovering a cure for peanut allergies is crucial. Symptoms of an allergic reaction – such as anaphylaxis, leading to the inability to breathe – can be life-threatening and occur rapidly. While EpiPens are used to control general allergic reactions, there is no specific treatment available for peanut allergies – until … Continue reading A cure for peanut allergies in sight?
AquaBounty, a Massachusetts-based company, began growing genetically modified (GM) salmon nearly three decades ago. However, it wasn’t until 2015 that the FDA approved the fish for human consumption. Health Canada made the same decision in 2016. While a current law prevents US sales until a labeling system is established, Canada has imported roughly 5 tons of the GM salmon since May 2016. Although the fish sell unlabeled, Canadians appear to be embracing the next frontier in aquaculture. Continue reading Canadians bringing genetically modified salmon to their tables
Results from a small clinical trial comprising 86 cancer patients have prompted scientists to rethink how different cancers are classified and treated. The drug being assessed was Keytruda, a recent addition to oncologists’ arsenal of cancer immunotherapy drugs. Unlike traditional chemotherapies, which poison and kill cancer cells directly, cancer immunotherapy recruits the body’s own self-defense machinery to attack tumors. Although our immune systems are very good … Continue reading Turning the Immune System into an Equal Opportunity Cancer Killer