DNA Detectives: How scientists are using DNA from the environment to see the unseen

by Sanjana Kulkarnifigures by Swathy Karamchedu Forensic DNA testing has become crucial in criminal investigations and legal proceedings. DNA has linked people to crime scenes using hair or blood and exonerated wrongfully convicted individuals. This type of DNA is called environmental DNA (eDNA) because it is collected from the environment, rather than from a person. Scientists have also begun analyzing eDNA from non-human organisms. All … Continue reading DNA Detectives: How scientists are using DNA from the environment to see the unseen

Biodiversity Loss Can Increase the Spread of Zoonotic Diseases

by Sanjana Kulkarni SARS-CoV-2 may have spread to humans from an animal host, but it is not the only disease-causing agent (i.e. pathogen) to have done so. Lyme disease, Ebola virus, influenza, HIV, the plague, and rabies virus are just some examples of zoonotic diseases, meaning that they originated in animals and spread (i.e spilled over) to humans.  Many human activities, such as deforestation and … Continue reading Biodiversity Loss Can Increase the Spread of Zoonotic Diseases

Mining DNA for Disease Prediction: The polygenic risk score

by Alex Yenkinfigures by Allie Elchert Long before the completion of the Human Genome Project, scientists knew that many common diseases had a genetic component. However, there was debate about the architecture of these genetic effects: were there a few high-effect mutations or thousands of tiny effect mutations spread throughout the genome? Now, in the full swing of the genomics revolution, we can see that … Continue reading Mining DNA for Disease Prediction: The polygenic risk score