Mining DNA for Disease Prediction: The polygenic risk score

by Alex Yenkinfigures by Allie Elchert Long before the completion of the Human Genome Project, scientists knew that many common diseases had a genetic component. However, there was debate about the architecture of these genetic effects: were there a few high-effect mutations or thousands of tiny effect mutations spread throughout the genome? Now, in the full swing of the genomics revolution, we can see that … Continue reading Mining DNA for Disease Prediction: The polygenic risk score

Computational models show why staying home really is the best idea

COVID-19 has now forced most of us into our homes for weeks. A recent study highlighted the importance of staying at home in these crucial times, even if you’re feeling well: people with mild, limited or even no symptoms at all were estimated to have caused the majority of severe COVID-19 infections and the wide geographic spread of COVID-19. Continue reading Computational models show why staying home really is the best idea

COVID-19 and Emerging Viral Diseases: the journey from animals to humans

by Ziqi Chen figures by Rebecca Senft We live in a universe of viruses. It is estimated that there are billions of types of viruses on earth, and ~320,000 types that infect mammals alone. Many viral species exist in our surrounding environment. As we live, breathe, eat, talk, and go about our daily activities, the number of viruses that we come into contact with is virtually … Continue reading COVID-19 and Emerging Viral Diseases: the journey from animals to humans

From Genes to Disease: the release of the UK Biobank

by Layla Siraj figures by Rebecca Senft Imagine if you could tell, through some combination of your environment and your genetics, what illnesses you might develop. This could give you the ability to either prevent these illnesses before they even happen or catch and treat the illnesses early enough to prevent long-lasting effects. This reality is one step closer with the release of the UK … Continue reading From Genes to Disease: the release of the UK Biobank