Efficient drug delivery platform into the brain

Treatment of neurological disorders, such as Parkinson’s disease and stroke, has always been a challenging task, partly due to the existence of the blood-brain barrier (BBB). The BBB is a border that separates the blood circulation from the surrounding brain tissue. In a healthy brain, the BBB only allows the passage of nutrients crucial to brain function, while restricting the transportation of other substances, including … Continue reading Efficient drug delivery platform into the brain

Treating knee osteoarthritis with a nanoparticle injection

Osteoarthritis is a joint disease that occurs when the cartilage (the flexible and slippery tissue that protects the ends of bones in the joints) wears away, causing bones to rub against each other. Common causes of osteoarthritis include aging, sports injuries, and excess body weight. Scientists from Tsinghua University and Shanghai Jiao Tong University have developed nanoparticles that can be injected as lubricant into the … Continue reading Treating knee osteoarthritis with a nanoparticle injection

China’s Genetically Edited babies: What really happened?

A Chinese researcher, He Jiankui, shocked the world two weeks ago when he revealed that the world’s first genetically edited babies had been born. Jiankui claimed to have edited embryos before implanting them into the mother as part of an otherwise routine in vitro fertilization (IVF) procedure. Since his bold announcement via YouTube, the scientific community at-large – both in the United States and in … Continue reading China’s Genetically Edited babies: What really happened?

Making Steak out of Spinach: How bioengineering could change meat production

by George Touloumes figures by Brad Wierbowski Would you ever consider eating meat that was grown in a lab instead of raised on a farm? What if it were both healthier and more sustainable than conventional meat? Silicon Valley venture capital firms and major meat companies like Tyson Foods are now investing tens of millions of dollars in bioengineering research to produce exactly that kind … Continue reading Making Steak out of Spinach: How bioengineering could change meat production

Human blood cells

Scientists Learn to 3D Print Cells One Drop at A Time

3D printing is poised to become a major technological advancement in treating injuries and illnesses that cause tissue damage. For scientists, creating artificial tissue with 3D printing has been a challenge. As the 3D printed structure grows in size, cells often move and compromise the tissue’s structural integrity. New work from Oxford University addresses this problem. By encasing cells in nanoliter sized droplets of fat molecules, researchers are able … Continue reading Scientists Learn to 3D Print Cells One Drop at A Time

From Seed to Organ: Growing a Liver

Over 17,000 Americans are currently waiting for liver transplants, with millions more living with chronic liver disease. There simply aren’t enough healthy organs to go around. So why not engineer them? Growing a liver “from scratch” by using its constituent cells could replace the need for whole organ transplants. Researchers at the Massachusetts Institute of Technology generated hydrogels containing three different types of human cells, … Continue reading From Seed to Organ: Growing a Liver

The war on malaria gets a new weapon: a toxic fungus

As mosquitoes develop resistance to insecticides used to control their populations, scientists have been developing new tools. The latest idea: infecting mosquitoes with a fungus genetically engineered to produce arachnid toxins. After infecting the mosquitoes with fungal spores, the bugs showed increase mortality within 2.5 days after exposure and fed less in the days before their death, compared to their healthy counterparts. Continue reading The war on malaria gets a new weapon: a toxic fungus

Streamlined 473-Gene Bacteria May Lead to Discoveries, Biochemical Production

Scientists at the J. Craig Venter Institute have created a fast-growing bacterial cell with a nearly-minimal number of genes necessary for survival – just 473 in total. These genes were entirely synthesized – not transplanted from a grown organism – and the creation of such a cell may allow big steps forward in gene function identification and efficient mass-production of biological molecules. Continue reading Streamlined 473-Gene Bacteria May Lead to Discoveries, Biochemical Production

Friend or Foe? Getting the body to make peace with bioengineered drug delivery systems

Recent drug discoveries promise new treatments and cures for many diseases. However, getting a drug to work, not only in experiments with cells in the lab, but also in the human body, is difficult. One challenge? Getting past the body’s line of defense, the immune system, which fights foreign invaders that make it into the body. In September, a news article reported that scientists have … Continue reading Friend or Foe? Getting the body to make peace with bioengineered drug delivery systems

Challenging Evolution: How GMOs Can Influence Genetic Diversity

by Heather Landry Summary: The vast diversity in gene sequences are what create the large variety of plants and animals we see today. Genetic diversity is crucial for adapting to new environments, as more variation in genes leads to more individuals of a population having favorable traits to withstand harsh conditions. Low genetic diversity, on the other hand, can be very problematic during changing environments, … Continue reading Challenging Evolution: How GMOs Can Influence Genetic Diversity