New markers for dementia risk could pave the way for the development of blood-based methods for diagnosing and screening for dementia. This provides an opportunity to identify and diagnose at-risk populations earlier. Continue reading New blood-based markers for dementia risk identified
Scientists have discovered a new way to study Alzheimer’s disease in mice, revealing how brain cells die in AD. This breakthrough could lead to new treatments that slow or stop the disease. Continue reading Hope for New Alzheimer’s Treatments as Scientists Discover How Brain Cells Die
by Gizem Terzioglufigures by MJ Park Alzheimer’s disease is a progressive neurodegenerative disorder that affects millions of people worldwide, and despite years of research efforts, there is still no cure. However, recent studies have highlighted the crucial roles of microglia, the resident immune cells of our brain, in the development and progression of Alzheimer’s disease. But the question remains: do microglia defend our brain against … Continue reading Are microglia the hero or the villain in Alzheimer’s disease?
Measuring proteins in neuronal-derived extracellular vesicles in the blood may serve as a biomarker for Alzheimer’s Disease. Continue reading Neuronal extracellular vesicles in blood may predict Alzheimer’s Disease
by Muhammet M. Ozturkfigures by Wei Wu For decades, scientists have been intrigued by how the brain controls the body. This curiosity led them to discover neurons, the brain’s messenger cells. Neurons, which receive, transmit, and process information, are arguably the most famous cells in our brain. The attention they get might suggest that the brain is only made up of neurons. However, about half … Continue reading Microglia: The protectors of the brain
Results from a phase 2 clinical trial reveal that a new two-drug therapy for ALS can slow disease progression by six weeks over a six-month period. This therapy could possibly improve lifespan and quality of life, and may be effective in other neurodegenerative disorders as well. Continue reading Slowing ALS with a Two-Drug Therapy
Scientists have uncovered a new mechanism by which important components of cells can be damaged. Such a discovery could provide new insight into the biology of aging, cancer, and degeneration, as well as development of new drugs and strategies for food preservation. Continue reading A Radical New Mechanism for Cell Damage
Electrical recordings from human subjects have revealed the existence of memory-trace cells, which change their response depending on which previous experience is supposed to be recalled, providing a major insight into how the brain remembers specific events. Continue reading Learning to Remember: Memory-Trace Cells
Drugs that inhibit formation of protein clumps may help treat degenerative diseases, but determining when to administer them is challenging. Using mathematical modelling, researchers have developed a strategy to design better treatment protocols based on individual drug properties. Continue reading Mathematical Modeling to Treat Degenerative Diseases
Rather than try to get a glimpse into the brain, which is notoriously difficult, a new study shows that signs of Alzheimer’s disease may appear in the blood, which is a lot more accessible. Continue reading The future of Alzheimer’s disease detection could be as simple as a blood test