by Muhammet M. Ozturkfigures by Wei Wu For decades, scientists have been intrigued by how the brain controls the body. This curiosity led them to discover neurons, the brain’s messenger cells. Neurons, which receive, transmit, and process information, are arguably the most famous cells in our brain. The attention they get might suggest that the brain is only made up of neurons. However, about half … Continue reading Microglia: The protectors of the brain
Results from a phase 2 clinical trial reveal that a new two-drug therapy for ALS can slow disease progression by six weeks over a six-month period. This therapy could possibly improve lifespan and quality of life, and may be effective in other neurodegenerative disorders as well. Continue reading Slowing ALS with a Two-Drug Therapy
Drugs that inhibit formation of protein clumps may help treat degenerative diseases, but determining when to administer them is challenging. Using mathematical modelling, researchers have developed a strategy to design better treatment protocols based on individual drug properties. Continue reading Mathematical Modeling to Treat Degenerative Diseases
A group of scientists uncovered a commensal gut bacteria, Akkermansia muciniphila, that can significantly ameliorate ALS symptoms in mice, and also prolong their lifespan. Their results highlight the potential of modulating the gut microbiome to treat ALS. Continue reading The Next Ice Bucket Challenge: Modulating Your Gut Microbiome to Treat ALS
Who would have guessed that pouring ice water on one’s head would lead to $94.3 million in donations (and counting) to fund Amyotrophic lateral sclerosis (ALS) research? Well it did. And it’s a great thing – ALS is a devastating neurodegenerative disease in which progressive death of motor neurons causes debilitating and eventually fatal paralysis. There are no cures and very few therapies available. However, … Continue reading What can funding for ALS research do? A recent study reports a new therapeutic target