Small-Molecule Probes: Bridging the gap between understanding and curing disease

by┬áMichael Vinyard figures by Jovana Andrejevic and Michael Vinyard Why do we have cures and medicines for some diseases but not others? Surprisingly, it is not because we cannot make the medicines; it is because we do not know enough about the diseases that need new medicines. To span the chasm between understanding the biology of a disease and successfully treating patients, we must foster … Continue reading Small-Molecule Probes: Bridging the gap between understanding and curing disease

EBC-46, a novel PKC inhibitor shows pre-clinical potential

New cancer drug promising, but has a long way to go

A recent article published in Medical Express last week touts the impressive findings of a pre-clinical study on the experimental drug EBC-46 (pictured above). In the article, they claim that EBC-46 is able to effectively destroy tumors by destroying the blood vessels that supply it with oxygen and nutrients. It is important, however, to remember that the work they are reporting on is very preliminary … Continue reading New cancer drug promising, but has a long way to go