Researchers from Kyoto University in Japan started a clinical trial this month to treat Parkinson’s disease with reprogrammed stem cells. This follows the successful restoration of brain cell function in monkeys using these stem cells reported last year. Parkinson’s disease is characterized by the loss of a specific type of neuron in the brain, called dopaminergic neurons, which make the essential neurotransmitter dopamine. The reduced … Continue reading World’s first clinical trial to treat Parkinson’s disease with stem cells
Early-stage research has identified a compound that stops pesky colds in their tracks – useful as a potential cold cure. Although adults are bothered by an average of 2-3 colds per year, colds can “cause serious complications in people with conditions like asthma and [chronic obstructive pulmonary disease] (COPD),” lead researcher Edward Tate, Chemical Biology Professor at the Imperial College London, told ScienceDaily. “A drug … Continue reading A Future Cure for the Common Cold?
Progressive blindness has been reversed in two patients with age-related macular degeneration, also known as AMD. AMD is a leading cause of blindness in people over 50. AMD damages the central portion of the retina, called the macula, which decreases vision over time, and can lead to blind spot formation. Phase 1 clinical trial results highlighting the effectiveness of a stem cell-based therapy were published … Continue reading Promising results for a treatment for blindness
For as long as humans have conceived of making hybrid organisms, an ethical debate has been waged over whether or not we should. The pros and cons are vast and poignant. Each new scientific advancement towards making hybrids stokes the fire of controversy. This year, researchers presented work at a conference detailing the most recent hybrid: a sheep-human chimera. To create these chimeras, scientists used … Continue reading Scientists have created sheep that are 0.01% human
No, we won’t be seeing designer babies anytime soon. But scientists have successfully cloned monkeys for the first time, establishing a technique that could be used to create better disease models using primates, the closest animals to humans. These cloned monkeys, Zhong Zhong and Hua Hua, are alive and well in China. They were created using the same technology (somatic cell nuclear transfer) used to … Continue reading Monkey see, monkey do: scientists have created the first cloned primates
Developing cancer drugs is challenging. Often, scientists will find a drug that kills cancer cells in a petri dish but fails to act on an actual tumor. Ravid Straussman from the Weizmann Institute of Science and Todd Golub from Harvard Medical School think that in situ, bacteria can protect cancer cells from drugs. To test their theory, Staussman and Golub mixed some healthy skin cells with cells from a … Continue reading Bacteria May Help Protect Cancer Cells
Glioblastoma is one of the most deadly brain cancers because it is nearly impossible to destroy the cause of the cancer: cancerous stem cells. However, scientists are using Zika’s preference for stem cells to target and eliminate the cancerous stem cells in adults. The preliminary study shows the viability of this method, but more thorough research and a PR campaign may be necessary before Zika treatments for brain cancer can become standard protocol. Continue reading Could Zika become a treatment for brain cancer?
3D printing is poised to become a major technological advancement in treating injuries and illnesses that cause tissue damage. For scientists, creating artificial tissue with 3D printing has been a challenge. As the 3D printed structure grows in size, cells often move and compromise the tissue’s structural integrity. New work from Oxford University addresses this problem. By encasing cells in nanoliter sized droplets of fat molecules, researchers are able … Continue reading Scientists Learn to 3D Print Cells One Drop at A Time
What is the difference between a normal cell and a cancer cell? The answer lies in their DNA. Cancer results from the accumulation of genetic mutations, which trigger uncontrolled cell growth. Cancer’s mutated DNA can reveal its presence early on in the disease. Like leaving fingerprints at a crime scene, tumor cells release small pieces of DNA into the bloodstream. This “circulating tumor DNA” can now … Continue reading Catching Cancer: Blood Test for Early-Stage Diagnosis
A medical team at Johns Hopkins University genetically engineered a common cold virus to deposit a gene when injected into the human eye. This gene codes for a protein that binds to VEGF, another protein whose activity in old age contributes to vision loss (a disease called AMD or wet AMD). This small clinical study’s preliminary results show that just one small dose is potent enough to improve a patient’s vision loss. Continue reading Genetically engineered viruses: a medicine of the future