Researchers at McMaster University have developed a novel method for stabilizing vaccines, removing the strict requirement that the components be maintained within a specific low temperature range from development through delivery. The technique is based on drying the vaccines using two FDA-approved sugars and was shown to be successful in preserving vaccine effectiveness at elevated temperatures for twelve weeks. While it must still be validated on other vaccines, this method could be a major step toward cheap, accessible immunization in developing areas. Continue reading A Sweet Solution for Preserving Vaccines
While you are likely familiar with the annoying experience of being a mosquito’s ‘meal of the day’, more is going on behind the scenes of that insect bite than meets the eye. Mosquitoes, which are drawn to human scent and breath, require proteins from the blood of their victims to develop their eggs and reproduce. This sounds harmless enough, but mosquitoes also excel at picking … Continue reading New Drug May Prevent Mosquitoes From Wanting to Bite You
Alzheimer’s disease is the leading cause of dementia. It progressively worsens multiple aspects of health over time, from short-term memory loss to behavioral changes to loss of bodily functions. The actual cause of Alzheimer’s is currently unknown. One widely-accepted hypothesis proposes that Alzheimer’s is caused by the accumulation of misfolded proteins in the brain. Unfortunately, many drugs targeting misfolded proteins perform poorly in clinical trials, … Continue reading Oral bacteria may be responsible for Alzheimer’s disease
Influenza A is the virus responsible for the Spanish Flu pandemic, which wiped out 3-5% of the human population in the early 20th century. The annual influenza outbreak occurs in the autumn and winter, although it is not normally deadly for healthy adults. There is currently no vaccine providing permanent protection against influenza A because the virus mutates and changes so often, requiring a yearly … Continue reading The Actual Master of Disguise: The Flu
We have come a long way in treating HIV over the past two decades. By following a strict drug regimen, an HIV positive patient can stave off the onset of AIDS for many years. These drugs are expensive, however, and they come with side-effects. Furthermore, noncompliance with the drug regimen can have serious and long-lasting impacts on the patient’s health. Preventing HIV infection is both … Continue reading PrEP: Preventing HIV Infection Before It Starts
If you’ve visited a supermarket recently, you might have noticed that yogurts and kombucha are taking up more shelf space. These products are two popular examples of probiotics: living bacteria touted to provide human health benefits. It’s not just a millennial fad – the probiotics market is projected to be over $60 billion by 2023. The accepted belief is that good bacteria drive out bad … Continue reading Probiotics prevents dangerous pathogen infection by making the bacteria ‘deaf’
In order to adapt to their environments, it is important that bacteria be able to mix up their genetic code. One way that bacteria do this is by taking up bits of free-floating foreign DNA that can be released by other kinds of bacteria into their environments when they die. This process is called ‘transformation.’ The pieces of DNA can occasionally encode components that make … Continue reading Bacteria snatch up foreign material using specialized arm-like structures
Antibiotic resistance is a rampant problem around the world. More than 23,000 deaths a year in the US are a result of antibiotic resistant bacteria. Bacteria become resistant to antibiotics in several ways. The antibiotic itself can be broken down, or the components of bacteria targeted by antibiotics can mutate. Over prescription leads to the development of further resistance. With each year there are increasing numbers … Continue reading Have antibiotic resistant bacteria met their match? A new method for antibiotic discovery that could change the arms race.
Glioblastoma is one of the most deadly brain cancers because it is nearly impossible to destroy the cause of the cancer: cancerous stem cells. However, scientists are using Zika’s preference for stem cells to target and eliminate the cancerous stem cells in adults. The preliminary study shows the viability of this method, but more thorough research and a PR campaign may be necessary before Zika treatments for brain cancer can become standard protocol. Continue reading Could Zika become a treatment for brain cancer?
As mosquitoes develop resistance to insecticides used to control their populations, scientists have been developing new tools. The latest idea: infecting mosquitoes with a fungus genetically engineered to produce arachnid toxins. After infecting the mosquitoes with fungal spores, the bugs showed increase mortality within 2.5 days after exposure and fed less in the days before their death, compared to their healthy counterparts. Continue reading The war on malaria gets a new weapon: a toxic fungus