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Next Seminar – April 5 – The Splice of Life: Cutting and pasting RNA in medicine and disease

April 5, 7-9 pm Pfizer Hall (directions) The intricate process of reading genes in our DNA to make proteins is arguably the most fundamental part of life. In this talk, we will dive into one critical step within this process, called RNA splicing. We will discuss what RNA splicing is, how splicing alternative forms of RNA leads to more protein diversity, and what happens when … Continue reading Next Seminar – April 5 – The Splice of Life: Cutting and pasting RNA in medicine and disease

Repatha's clinical trial involved over 27,000 patients and cost over $1 billion. ['The City' from Herry Lawford]

Heart Disease Drug Faces Biggest Test Yet

We just learned a lot more about a drug called Repatha, one of the newest weapons in the war against heart disease.  Heart-related diseases are the leading cause of death worldwide, accounting for over 30% of global deaths.  One of the major physiological warning signs of heart disease is “bad” cholesterol (LDL), which can clog arteries and increase the risk of heart attack and stroke. … Continue reading Heart Disease Drug Faces Biggest Test Yet

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Cancer Immunotherapy: Fighting fire with fire

by Kimberly Hagel figures by Alexandra Was We, as humans, tend to idealize that which is bigger, better, faster, and stronger. It is in our nature to strive towards the best. To improve. To win. Indeed, the penetrance of this mentality reaches to our very core, even to the individual cells of which we are composed. A prime example of this: cancer. Today, cancer is … Continue reading Cancer Immunotherapy: Fighting fire with fire

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TRAPPIST-1 and Earth’s distant cousins

The recent discovery of Earth-like planets in the TRAPPIST-1 system has been a major headline for the past few weeks. A team led by Michael Gillon found three planets in the TRAPPIST-1 system in 2016, and recently reported at least 4 more which may contain the appropriate elements for life. One of the strongest indicators that a planet could harbor life is if a planet’s … Continue reading TRAPPIST-1 and Earth’s distant cousins

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Spectrum

These colorful fractions were obtained upon purifying a synthetic small-molecule through flash column chromatography. Though most of these were impurities (bright colors in organic chemistry is usually not a great sign), it served as a reminder to appreciate the beauty in the mundane and seemingly unimportant. Contributed by Carmen Sivakumaren, a graduate student in the Biological and Biomedical Sciences Program at Harvard Medical School.   Continue reading Spectrum

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Opinion: Make the FDA Great Again? Trump and the future of the drug approval process

Update: Since the writing of this article, Donald Trump has picked Scott Gottleib as FDA commissioner. -SITN editorial staff by Linda Honaker figures by Rebecca Clements Donald Trump will soon pick a new commissioner for the Federal Drug Administration (FDA). The choice will likely be someone who will try to make the administration’s drug approval requirements less rigorous in order to get drugs on the … Continue reading Opinion: Make the FDA Great Again? Trump and the future of the drug approval process