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Tooth Decay: An epidemic in America’s poorest children

by Leah Rosenbaum Last April, Dr. Paul Reggiardo saw a patient who was referred to his dental office in Huntington Beach, California from the local emergency room. She was an eight-year-old girl with facial swelling, the soft tissue on her head puffy from infection. It was facial cellulitis, said Reggiardo, caused by an infected tooth. He sees multiple cases like this each year: an untreated … Continue reading Tooth Decay: An epidemic in America’s poorest children

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Turning the Immune System into an Equal Opportunity Cancer Killer

Results from a small clinical trial comprising 86 cancer patients have prompted scientists to rethink how different cancers are classified and treated. The drug being assessed was Keytruda, a recent addition to oncologists’ arsenal of cancer immunotherapy drugs.  Unlike traditional chemotherapies, which poison and kill cancer cells directly, cancer immunotherapy recruits the body’s own self-defense machinery to attack tumors.  Although our immune systems are very good … Continue reading Turning the Immune System into an Equal Opportunity Cancer Killer

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An Electrifying New Role for the Immune System in Heart Health

by Giulia Notarangelo figures by Rebecca Clements The human body fights off noxious intruders on a daily basis to maintain our health and prevent disease. The army of cells that is responsible for leading this fight is called the immune system. The immune system is comprised of a myriad of cells, each having their own defense strategy. Among these cells are the macrophages. As their … Continue reading An Electrifying New Role for the Immune System in Heart Health

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(2 x prime) + 1 = ? :The 200-year-old story of Sophie Germain and its 21st century legacy

by Qingbo Wang figures by Anna Maurer In 2014, the Fields Medal, often described as the “Nobel Prize of Mathematics,” was awarded to a Harvard alumnus and mathematician, Maryam Mirzakhani. The mathematics society celebrated not only her sophisticated theory of geometry and dynamical systems, but also the fact that she is the first female and Iranian to receive this prestigious prize. Although the news indicates … Continue reading (2 x prime) + 1 = ? :The 200-year-old story of Sophie Germain and its 21st century legacy

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Expanding the Antibiotic Arsenal: A New Drug of Last Resort

Prior to the discovery of antibiotics, bacterial infections were the leading cause of death worldwide. Now, treating infections is often a routine procedure – simply requiring a doctor’s visit and a prescribed antibiotic. However, this simple routine has become marred by the emergence of antibiotic resistance. The misuse and overuse of antibiotics is fueling the rise of resistant bacteria. In response to antibiotic exposure, bacteria have evolved … Continue reading Expanding the Antibiotic Arsenal: A New Drug of Last Resort

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Cancer Moonshot Musings II: Fusion oncoproteins in focus

by Steph Guerra figures by Shannon McArdel The Cancer Moonshot is an initiative that was launched by Joe Biden in 2016 with the goal of accelerating cancer research progress by bringing together world-class researchers and institutions in the battle against this disease. Armed with $300 million in startup funding, plus a total of $1.8 billion authorized over the next seven years, the Cancer Moonshot has … Continue reading Cancer Moonshot Musings II: Fusion oncoproteins in focus

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Strength in Numbers: genetic sequencing of large populations is shaping the future of medicine

by Ryan L. Collins figures by Brad Wierbowski Thanks to modern genetics, “precision medicine” is slowly becoming a reality: doctors can perform genetic tests to determine your risk for dozens of diseases, like stroke or liver disease, and can prescribe treatments or therapies tailored to your individual genetic makeup. Yet before doctors can provide you with precision medicine in practice, they first need to understand … Continue reading Strength in Numbers: genetic sequencing of large populations is shaping the future of medicine