CRISPR Cover-01

Is Genetic Surgery in My Future?: A conversation with Dr. John Doench about CRISPR and genome editing

by Christopher Gerry figures by Mike MacArthur The last few years have seen an explosion in our capacity to study the human genetic code. In particular, a technology called CRISPR/Cas9 has been at the forefront of many of these advances, capturing the imagination of scientists and the attention of the general public. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a type of bacterial self-defense … Continue reading Is Genetic Surgery in My Future?: A conversation with Dr. John Doench about CRISPR and genome editing

An isolated blue dna molecule on white background

First Human Trial of Gene Editing Technique CRISPR Approved

The first clinical trial using the gene editing technique CRISPR was given the go-ahead by panel from the US National Institutes of Health (NIH). The trial is aimed at determining if the technique is safe for use on human subjects. As there is much we have yet to learn about genes and their expression, it is a valid concern that modifying DNA in humans could … Continue reading First Human Trial of Gene Editing Technique CRISPR Approved

Mouse embryo

Gene editing emerges as a new therapeutic strategy for Duchenne muscular dystrophy

Advances in gene editing technology have spurred considerable progress towards a treatment for Duchenne muscular dystrophy (DMD).  Although the disease is rare – affecting roughly 1 in 5,000 male births – its consequences are devastating: patients are confined to wheelchairs at an early age and often succumb to heart or respiratory failure in their twenties or thirties.  No treatments are currently available, but three separate … Continue reading Gene editing emerges as a new therapeutic strategy for Duchenne muscular dystrophy