A now five-month-old boy was the first child to be born via spindle nuclear transfer, a controversial fertilization procedure that incorporates genetic material from three different people. Most of our genes are located in the DNA found in a cell’s nucleus, but a few reside in tiny compartments called mitochondria. While rare, mutations in mitochondrial DNA can result in devastating disorders that often cannot … Continue reading It’s a boy! Baby is born with DNA from three “parents”
“Shrink to grow” is a two-pronged business strategy where a company gets rid of unprofitable brands (“shrink”) to focus its resources on a few remaining or new brands (“grow”). Companies like P&G and Microsoft have used it, and a similar idea to “shrink to grow” is behind the George Church lab’s ongoing development of the synthetic bacteria rEcoli57. But while the executives at P&G were … Continue reading Shrink to grow: on the road towards a 57-codon bacterium
Scientists at the J. Craig Venter Institute have created a fast-growing bacterial cell with a nearly-minimal number of genes necessary for survival – just 473 in total. These genes were entirely synthesized – not transplanted from a grown organism – and the creation of such a cell may allow big steps forward in gene function identification and efficient mass-production of biological molecules. Continue reading Streamlined 473-Gene Bacteria May Lead to Discoveries, Biochemical Production
One of our Instagram followers won a print of this beautiful image! Be sure to follow us on Instagram @SITN_Harvard for your chance to win some SciArt. This beautiful contribution from Don Pottle is best described by the legend himself: “A few years ago, I was asked by a maker of contact lenses to examine a few samples of used contact lenses. There was a suspicion of … Continue reading Crystaleyes
Spitting into a plastic tube normally doesn’t cost $199, but the personal genomics company 23andMe has recently won FDA approval to turn that saliva into a DNA fingerprint. By identifying common variants in our genetic code, 23andMe’s DNA-testing service originally supplied personalized insights into disease predisposition, drug sensitivity, and other health-related traits. In 2013, however, the FDA demanded that 23andMe shutter the health-related aspect of … Continue reading 23andMe wins approval from FDA: What does your DNA say about you?
By Andrew Wong, a second year graduate student in the Applied Physics program at Harvard University. The increase in global energy demand and subsequent carbon dioxide emissions has driven advancements in renewable energy generation technologies such as wind turbines and solar cells. However, these technologies are inherently intermittent, and require robust energy storage devices. Inexpensive, large-scale energy storage systems such as aqueous … Continue reading The Light of Elendil in Shelob’s Lair
Recent drug discoveries promise new treatments and cures for many diseases. However, getting a drug to work, not only in experiments with cells in the lab, but also in the human body, is difficult. One challenge? Getting past the body’s line of defense, the immune system, which fights foreign invaders that make it into the body. In September, a news article reported that scientists have … Continue reading Friend or Foe? Getting the body to make peace with bioengineered drug delivery systems