Developing cancer drugs is challenging. Often, scientists will find a drug that kills cancer cells in a petri dish but fails to act on an actual tumor. Ravid Straussman from the Weizmann Institute of Science and Todd Golub from Harvard Medical School think that in situ, bacteria can protect cancer cells from drugs. To test their theory, Staussman and Golub mixed some healthy skin cells with cells from a … Continue reading Bacteria May Help Protect Cancer Cells
Glioblastoma is one of the most deadly brain cancers because it is nearly impossible to destroy the cause of the cancer: cancerous stem cells. However, scientists are using Zika’s preference for stem cells to target and eliminate the cancerous stem cells in adults. The preliminary study shows the viability of this method, but more thorough research and a PR campaign may be necessary before Zika treatments for brain cancer can become standard protocol. Continue reading Could Zika become a treatment for brain cancer?
What is the difference between a normal cell and a cancer cell? The answer lies in their DNA. Cancer results from the accumulation of genetic mutations, which trigger uncontrolled cell growth. Cancer’s mutated DNA can reveal its presence early on in the disease. Like leaving fingerprints at a crime scene, tumor cells release small pieces of DNA into the bloodstream. This “circulating tumor DNA” can now … Continue reading Catching Cancer: Blood Test for Early-Stage Diagnosis
Results from a small clinical trial comprising 86 cancer patients have prompted scientists to rethink how different cancers are classified and treated. The drug being assessed was Keytruda, a recent addition to oncologists’ arsenal of cancer immunotherapy drugs. Unlike traditional chemotherapies, which poison and kill cancer cells directly, cancer immunotherapy recruits the body’s own self-defense machinery to attack tumors. Although our immune systems are very good … Continue reading Turning the Immune System into an Equal Opportunity Cancer Killer
by Steph Guerra figures by Shannon McArdel The Cancer Moonshot is an initiative that was launched by Joe Biden in 2016 with the goal of accelerating cancer research progress by bringing together world-class researchers and institutions in the battle against this disease. Armed with $300 million in startup funding, plus a total of $1.8 billion authorized over the next seven years, the Cancer Moonshot has … Continue reading Cancer Moonshot Musings II: Fusion oncoproteins in focus
by Kimberly Hagel figures by Alexandra Was We, as humans, tend to idealize that which is bigger, better, faster, and stronger. It is in our nature to strive towards the best. To improve. To win. Indeed, the penetrance of this mentality reaches to our very core, even to the individual cells of which we are composed. A prime example of this: cancer. Today, cancer is … Continue reading Cancer Immunotherapy: Fighting fire with fire
by Benika Pinch Fancy a pill packed with bacteria? Researchers are investigating using genetically modified bacteria, taken in pill form, to treat human disease. Informally, they are called “designer probiotics”. But, unlike probiotics (microorganisms with known health benefits), they can’t be obtained via a serving of yogurt from your local supermarket. Rather, the bacteria in question are feats of genetic engineering and are specifically designed … Continue reading Microbial Physicians: Delivering drugs with bacteria