Antibiotic Persistence and Resistance

by Molly Sargen Antibiotics are drugs that kill or inhibit the growth of microbes, including bacteria and fungi. These drugs work by blocking essential processes like protein production, DNA replication, and cell division. After Alexander Fleming’s serendipitous discovery of Penicillin, antibiotics became a central feature of medical care. Today, antibiotics are used to treat a wide variety of infections and prevent new infections during invasive … Continue reading Antibiotic Persistence and Resistance

Mapping Individual Microbes among the Multitudes

by Sophia Swartzfigures by Jasmin Joseph-Chazan If you put all of the living things on Earth in a box–from humans to anteaters to teeny-tiny tardigrades–and then plucked one of these organisms out at random, it is very, very likely that you just found yourself a microbe. Microbes, although too small to be seen with the naked eye, are some of the most common forms of … Continue reading Mapping Individual Microbes among the Multitudes

Have antibiotic resistant bacteria met their match? A new method for antibiotic discovery that could change the arms race.

Antibiotic resistance is a rampant problem around the world. More than 23,000 deaths a year in the US are a result of antibiotic resistant bacteria. Bacteria become resistant to antibiotics in several ways. The antibiotic itself can be broken down, or the components of bacteria targeted by antibiotics can mutate. Over prescription leads to the development of further resistance. With each year there are increasing numbers … Continue reading Have antibiotic resistant bacteria met their match? A new method for antibiotic discovery that could change the arms race.

Fighting Fire with Fire: Killing bacteria with virus

by Veerasak “Jeep” Srisuknimit figures by Jovana Andrejevic Our time with antibiotics is running out. In 2016, a woman in Nevada died from a bacterial infection caused by Klebsiella pneumoniae that was resistant to all available antibiotics. Bacteria that is resistant to colistin, an antibiotic of last resort, has been discovered on pig farms in China. Bacteria have been evolving to resist antibiotics faster than … Continue reading Fighting Fire with Fire: Killing bacteria with virus

Expanding the Antibiotic Arsenal: A New Drug of Last Resort

Prior to the discovery of antibiotics, bacterial infections were the leading cause of death worldwide. Now, treating infections is often a routine procedure – simply requiring a doctor’s visit and a prescribed antibiotic. However, this simple routine has become marred by the emergence of antibiotic resistance. The misuse and overuse of antibiotics is fueling the rise of resistant bacteria. In response to antibiotic exposure, bacteria have evolved … Continue reading Expanding the Antibiotic Arsenal: A New Drug of Last Resort

MRSA Bacteria

Reversing Resistance: How to teach old antibiotics new tricks

It’s an all-too-common refrain nowadays, but antibiotic resistance remains one of the world’s most severe public health threats.  Bacteria have developed resistance to nearly every antibiotic drug in our arsenal, and the Healthcare Infection Society has estimated that 10 million people will die annually from antibiotic-resistant bacteria by 2050. Hoping to reverse these worrying trends, researchers from Oregon State University and Sarepta Therapeutics have developed … Continue reading Reversing Resistance: How to teach old antibiotics new tricks

Say Goodbye to Antibacterial Soaps: Why the FDA is banning a household item

by Gabriel W. Rangel figures by Michael Gerhardt How many times per day do you wash your hands? Do you ever think about the type of soap you use? We all know handwashing with soap is an impactful way to maintain health by decreasing the risk of becoming infected with one germ or another. Therefore, using soap with antibacterial compounds added is a no-brainer, right? … Continue reading Say Goodbye to Antibacterial Soaps: Why the FDA is banning a household item

An Alternative to Antibiotics?

Scientists offer an alternative method to fight bacteria in an effort to combat antibiotic resistance. They generated liposomes, or very small particles that look much like cell membranes. Because of this similarity, liposomes, instead of the host cells, can draw in bacterial toxins and allow the resulting non-toxic bacteria to be defeated by the body’s natural immune defense. However, this is just the beginning- for … Continue reading An Alternative to Antibiotics?