Hope for Alzheimer’s patients? The first positive clinical trial results in years

In 2018, approximately 5.7 million Americans are living with Alzheimer’s dementia, a number that is expected to double within the next 30 years. Alzheimer’s disease causes memory loss, mood changes, and eventually difficulty speaking, swallowing, and walking. Currently, no medication exists that can slow or stop the progression of Alzheimer’s disease and no new treatments have been approved by the FDA in more than 15 … Continue reading Hope for Alzheimer’s patients? The first positive clinical trial results in years

Monoclonal antibodies

Blood test probes the immune system to diagnose Alzheimer’s disease

What can our immune system tell us about brain health?  Research from Rowan University suggests that the presence of particular antibodies, the means by which our bodies identify threats, can predict if mental decline is an early symptom of a neurodegenerative disease like Alzheimer’s.  The research team discovered a set of 50 antibodies that, in a proof-of-concept study, predicted whether a patient exhibiting mild cognitive … Continue reading Blood test probes the immune system to diagnose Alzheimer’s disease

The spreading confusion: Rethinking Alzheimer’s disease

by Danielle Heller Proteins are molecular machines. They perform an incredible diversity of tasks that enable all living cells to function.  Like any machine, a protein must be properly assembled in order to carry out its specific task, and if something goes awry, the cellular consequences can be dire. Take Alzheimer’s disease for example. Alzheimer’s disease is the most common neurodegenerative disorder, affecting over 5 … Continue reading The spreading confusion: Rethinking Alzheimer’s disease

Neurons

Inhibiting Immune Cells: A New Strategy for Preventing Alzheimer’s Disease

Recent findings from Duke University have implicated overactive immune cells as a potential cause of Alzheimer’s disease (AD).  The authors of this new study propose that AD can develop when immune cells in the brain overconsume an essential nutrient called arginine.  Previous research in this field has primarily studied amyloid, the protein that composes the characteristic plaques found in the brains of AD patients.  Focusing … Continue reading Inhibiting Immune Cells: A New Strategy for Preventing Alzheimer’s Disease

Activities of 8 place cells recorded while the rat ran back and forth through along the track. Each dot is an action potential, and each color is a different cell. Credit Stuartlayton via Creative Commons 3.0

The recent Nobel Prize was not about solving Alzheimer's disease

(A response to ‘Alzheimer’s Disease Discovery Leads To Nobel Prize‘ and other similar articles) Activities of 8 place cells recorded while the rat ran back and forth through along the track. Each dot is an action potential, and each color is a different cell. Credit Stuartlayton via Creative Commons 3.0 Last week, the Nobel Prize in Physiology or Medicine was awarded for the discovery of … Continue reading The recent Nobel Prize was not about solving Alzheimer's disease