The modern challenges of combating malaria
— From a distance, malaria looks like a disease that we should have eradicated by now. Scientists have known for many years that most dangerous malaria cases are caused by the Plasmodium falciparum parasite. This parasite is transmitted to humans through the bite of an Anopheles mosquito, and has a complicated but well-understood lifecycle within its human host, involving invasion of both the liver and the blood. In humans, malaria causes fever, vomiting, headaches, and general achiness, but complications including brain damage, seizures, and red blood cell damage are responsible for most human deaths. With so many potential places to target malaria treatment – in the human liver, in human blood, or in the mosquito that carries the parasite from person to person – why did it still kill 655,000 people in 2010? Continue reading The modern challenges of combating malaria